Frontiers in human and veterinary antibody discovery
The Pirbright Institute hosted the inaugural Comparative Veterinary Immunology Group (CVIG) meeting Frontiers in Human and Veterinary Antibody discovery on 26 and 27 November,...
Interrupting cholesterol pathway reduces Marek’s disease spread
In a new discovery, scientists from The Pirbright Institute confirm that cholesterol production and transport play a crucial role in how Marek’s disease virus...
Poultry expertise at IDEXX
In a rapidly evolving poultry production environment with fewer treatment options, disease prevention and identification are more important than ever. Reliable lab diagnostics play...
Sample management and handling for diagnostic testing
Diagnostic testing is an important and widely used tool in commercial poultry husbandry. A key to best use of diagnostic testing, is to begin...
Key global health issues in cage-free and organic laying hens
In USA and Europe there has been a growth in cage-free, free range, and organic production over the last 10 years.
The percentage of all...
Researchers examine the role of APEC in turkey cellulitis
USPOULTRY and the USPOULTRY Foundation announce the completion of a funded research project at the University of Georgia in Athens, Georgia, in which researchers...
Linear Epitope Mapping of B-cell responses following immunization with Avian Reovirus S1133
Avian reovirus is a causative agents of tenosynovitis and viral arthritis. Commercially available reovirus vaccines do not protect against challenge with emerging variants associated...
The cost of mycoplasma infection in poultry
Sometimes some Mycoplasma infections cause disease in poultry and this has been extensively studied and worried about by veterinarians, poultry producers and veterinary authorities....
Monitoring of IBV circulation and prevalence
Infectious bronchitis (IB) is one of the most common viral diseases in chicken production worldwide and IB virus (IBV) is considered the most contagious...
A new view of how class I molecules fight diseases
Classical class I molecules of the major histocompatibility complex (MHC) play crucial roles in defence against viruses.
The class I molecules bind pieces of protein...
Biosecurity measures and new vaccines to combat the spread of bird flu
The recent H5N6 bird flu outbreak is confined to the south of England, partly due to the introduction of an Avian Influenza Protection Zone...
Increased cecal butyrate concentrations protect against Salmonella Enteritidis
Butyrate is a molecule that is extensively studied as a feed additive to improve gut health and animal performance. It also has been described...
Pathogenesis of egg infections by Salmonella – First Part
Salmonella is an invasive bacterial genus and colonizes the gut of chickens, and systemically spreads to internal organs, including the reproductive tract, potentially leading...
Future of coccidiosis management in turkeys
Coccidiosis is a disease that is caused by protozoan parasites that develop within the intestine of most domestic and wild animals and birds. Coccidia...
Holistic view of intestinal health in poultry
The intestinal health of poultry has broad implications for the systemic health of birds, animal welfare, the production efficiency of flocks, food safety, and...
Pathogenesis of egg infections by salmonella – Second Part
Early protection has been demonstrated after primary live vaccine administration early post-hatch but this effect is serotype-specific, while cross-protection between some serotypes has been...
The effects of diet and epigenetic alterations on the gut microbiome, inflammation and poultry...
The gut microbiota is a fundamental force influencing diverse aspects of avian physiology. Microbiome studies are at a critical juncture and facing a challenging...
How a single Avian Influenza protein can increase period of infection
New research led by scientists at The Pirbright Institute has shown how an Avian Infuenza a virus protein, called PB1-F2, is able to shut...
Comparison of four injection sites for Se bacterin vaccine in commercial pullets
As commercial pullets farming transitions from rearing a bird on a single level in conventional-style housing to rearing a bird in a multi-level aviary,...
Microbiota studies in poultry
The microbial populations that inhabit the gastrointestinal tract (GIT) of birds play an important role in the establishment and maintenance of a healthy gut....
The Salmonella initiative
An enduring challenge and reputational issue for the egg industry is caused by the presence of Salmonella enterica serovars (particularly some Typhimurium serotypes), which...
Infectious bronchitis virus (IBV) vaccines produced in eggs have unpredictable mutations
Scientists at The Pirbright Institute have shown that infectious bronchitis virus (IBV) vaccines produced in eggs have unpredictable mutations which may be prone to...
Turkey arthritis reovirus. Diagnostic strategies
Avian reoviruses (ARVs). They are non-enveloped viruses of 70-80 nm size having an icosahedral symmetry. The viral genome has 10 segments of double stranded...
Host and microbial biomarkers for intestinal health and disease in broilers
New tools can be used to determine the gut health status of animals and to predict animal performance or to make a decision whether...
On-farm control of campylobacter
Campylobacteriosis, primarily caused by the consumption of contaminated chicken products, accounts for the majority of food poisoning cases in Europe and many other developed...
Poultry gut health critical to NAE production
The production of “No Antibiotics Ever” (NAE) poultry is a common trend worldwide today. Despite scientific evidence indicating that specific antibiotic growth promoters (AGP)...
Pulsed ultraviolet light processing of eggs
In recent years, pulsed ultraviolet light has been shown to reduce microbial pathogens on the surface of shell eggs, crucial for maintaining good chick...
Characterizing litter mite communities. Applications of DNA barcoding for management strategies
The use of DNA barcoding can facilitate rapid biodiversity assessments of fastidious taxa - litter mite communities - by delineating species using molecular operational...
Microbiological consequences of different housing systems for laying hens, with particular reference to Salmonella...
A significant proportion of human illnesses caused by Salmonella are linked to the consumption of contaminated eggs. In response, substantial government and private industry...
Antimicrobial drug resistance in poultry. What do we know about risk factors?
There is an increasing amount of published surveillance and diagnostic submissions data, providing information on prevalence and trends of antimicrobial drug use and antimicrobial...
Biological control of Salmonella in the poultry industry: a European perspective
Salmonella remains one of the most important foodborne bacterial pathogens worldwide, and is frequently linked with the consumption of contaminated poultry meat and eggs....
Salmonella prevention strategies and influences of sampling method selection
Multiple factors can influence both Salmonella prevalence and diversity of Salmonella serogroups detected from both pre and post-harvest samples. Sampling methodologies vary widely when...
The challenges and future of poultry diagnostics
A review of the past helps to frame the future of poultry diagnostics. In the United States, the Land-Grant universities provided a fertile environment...
The role of feed additives in the protozoal diseases in poultry
Coccidiosis and histomoniasis are economically significant diseases in chickens and turkeys. Management, vaccination and medication are key tools in the control of these diseases...
Analysis of anti-Ascaridia galli antibody levels in egg yolk to detect parasite infection in...
In recent years, in response to consumer concerns regarding welfare of birds, there has been a move from caged to free-range production systems. This...
Improving birds’ health by refining their intestinal microbiota health and stability
Intestinal systems of living organisms are inhabited by a dense community of microorganisms dominated by bacteria but also containing archea, fungi, protozoa and viruses....
Gut health, intestinal innate immunity and performance
Gut health is a very important determinant for health and performance in particular in production animals. The intestinal innate immune system is pivotal in...
Ability to detect Salmonella vs. Salmonella-Free in poultry processing
Poultry are sampled often for Salmonella during growout on the farm and throughout the processing plant. While on farm sampling is not currently a...
Heat stress causes inhibition of Eimeria replication in broilers
Eimeria infection is one of the most important diseases affecting poultry production, and is characterized by bloody or watery diarrhea, weight loss, poor feed...
Active and passive Salmonella surveillance systems
Two surveillance systems have been established in France for the monitoring of antimicrobial resistance (AMR) in Salmonella enterica subsp. enterica isolated from the agro-food...
Major histocompatibility complex and genetic resistance to Infectious Bronchitis Virus
Infectious bronchitis virus (IBV) is an endemic disease of chickens responsible for considerable economic losses to the poultry industry worldwide. IBV replication leads to...
Case report: histomoniasis in broiler breeder pullets
Histomoniasis, commonly known as blackhead disease, is caused by an anerobic protozoan parasite, Histomonas meleagridis. Histomoniasis affects all gallinaceous birds and turkeys are the...
Quality Control Audits of killed vaccination
Vaccination programs for breeders and egg layers include procedures with inactivated vaccines. Killed (inactivated) vaccines are used to prevent disease in the vaccinated bird...
Alternatives to antibiotics in organic poultry
Organic poultry production is one of the fastest growing segments of organic agriculture with a 20% average annual increase since the establishment of the...
Better than alternatives to antibiotics
Many poultry flocks require antibiotic treatment, if not every cycle, regularly. Antibiotic alternatives are in great demand, especially in the context of dysbiosis and...
Histopathological evaluation of Histomonas meleagridis on ceca and the bursa of Fabricius in turkeys
Histomoniasis is caused by Histomonas meleagridis, a flagellated protozoan parasite. It causes systemic infection in turkeys and induces characteristic lesions in ceca and liver....
World Veterinary Day – celebrating the value of vaccination
The theme of this year’s World Veterinary Day – celebrated April, 27th – was Value of Vaccination. To celebrate it, some of the vaccinology...
Compatibility of a new multi-strain probiotic with a live-attenuated Salmonella vaccine in chickens
A pilot study was undertaken to assess the compatibility of a new multistrain probiotic with a live-attenuated Salmonella Typhimurium (ST) vaccine. Experimental units were...
Boosting the cell-mediated immunity in chickens post-hatch via pre-hatch delivery of nucleic acids
Respiratory virus infections such as Avian Influenza, infectious laryngotracheitis and infectious bronchitis lead to high morbidity and mortality in chickens globally.
Given the limitations...
Antibiotic-resistance: the contribution of the viruses in GIT microbiome
The GIT, or rather the gastro intestinal tract, is the organ of the all organism mostly colonized by the microbial population: it hosts more...
Isoquinoline alkaloids lower the prevalence of salmonella Heidelberg in broiler chickens
Worldwide, tens of millions human cases are reported every year for salmonellosis. This makes it one of the most common foodborne diseases, which can...
The declining trend of salmonellosis cases in the EU has levelled off
Cases of Salmonella Enteritidis acquired in the EU have increased in humans by 3% since 2014 says the report, which is compiled by the...
Infectious bronchitis virus shuts down cell stress signals
A new study from scientists at The Pirbright Institute and collaborators at the University of Surrey provides evidence that infectious bronchitis virus (IBV) can regulate the...
Enhancing biosecurity using flow analysis and Danish entry concepts
The term Danish entry is commonly used to describe entryways to livestock buildings that help people enter barns in a relatively bio secure way...
Bacterin usage
A good vaccination program, along with proper flock management and biosecurity, plays a key role in the health and productivity of broiler breeders. The...
Investigation of nutritional diseases at the veterinary diagnostic lab
Here below the role the veterinary diagnostic laboratory can play in helping to confirm nutritional diseases in a flock has been described. Regardless issues...
Use of injection syringes in the animal production industry
Animal health is an important factor to consider, as any disease outbreak can potentially have drastic economical consequences. For this reason, planning and preparing...
Gut health and Coccidiosis
In poultry, gut health is fundamental and the gastrointestinal tract accounts for twenty percent of the energy expenditure of the whole body. This energy...
Concurrent infection of Histomonas meleagridis and Eimeria meleagridis in a turkey flock
Blackhead disease (histomoniasis) in turkeys is one of the protozoan diseases sporadically documented in commercial turkey production facilities. Histomoniasis may induce mild, moderate, or...
Gut health in layers
To some extent gut health has not been a focus of commercial pullet and layer flocks unless the problem contributed to a significant mortality...
Detection and quantification of Gallibacterium anatis and Mycoplasma synoviae
Mycoplasma synoviae is one of the most common preconditions for secondary bacterial infections in poultry. It causes subclinical infections of the upper respiratory tract,...
How Marek’s disease may directly affect the chicken immune system
Marek’s disease virus (MDV) causes disease in chickens and is estimated to cost the global poultry industry up to US $2 billion each year.
In...
Salmonella, creating the most undesirable environment
Background
Salmonella non-typhoidal is among the top foodborne bacteria that cause illness within the United States annually.With 1.4 million illness (11% of foodborne bacteria), 19,336...
Footpad dermatitis in market turkey hens. Bird density and bedding material relationships
Lameness
and poor footpad condition can be major issues for meat-type poultry resulting
in their decreased well-being and decreased productivity. A large body of
research exists for...
Turkey dermatitis/cellulitis: where are we headed?
Clostridium septicum is a ubiquitous, spore-forming bacterium associated with spontaneous gas gangrene in both livestock and humans. The spores can persist in harsh environments,...
Maternal derived antibodies have a role on the impact of Original XPC
The objective of this study was to evaluate the role of maternally derived antibodies on the immune-modulatory capacity of XPC on antigen-specific humoral immune...
A multidisciplinary research approach on Avian Influenza in Italy
The Avian Influenza epidemic of 2016-2017 had been the largest in Europe in more than 10 years. The circulating virus was a Highly Pathogenic...
Infectious Laryngotracheitis (ILT) outbreaks in laying hens in Konya province
Infectious laryngotracheitis (ILT) epidemic cases characterized with respiratory symptoms, hemorrhagic tracheitis and laryngitis findings were identified in laying hen’s enterprises in Konya province.
Ten Lohman-breed...
Clinical coccidiosis in broilers with concurrent infection of Eimeria maxima and Eimeria praecox
Coccidiosis is a complex disease in chickens caused by protozoan parasites in the genus Eimeria. As Eimeria species are ubiquitous in poultry facilities, coccidiosis...
Protozoal management in turkeys
The two turkey protozoa that cause significant animal welfare and economic distress include various Eimeria species of coccidia and Histomonas meleagridis. For coccidia, oral...
Mycoplasma Synoviae, a technical update
Mycoplasma are the smallest free-living organisms both in size and number of genes, and unlike many other bacteria, they do not have a cell...
Novel Approach Improves Poultry Welfare by Reducing Stress on Chickens
MSD Animal Health (known as Merck Animal Health within the United States and Canada) recently announced the launch of EXZOLT® (fluralaner), the first systemic...
Backyard poultry flocks Salmonella spp. seroprevalence
As backyard poultry grows as a hobby in the United States there is an increased worry that poultry will become infected with Salmonella spp....
Avian reovirus, molecular characterization
Avian reovirus (ARV) is the main cause of viral arthritis and tenosynovitis in chickens and turkeys, triggering economic losses in the poultry industry due...
Managing CO2 and fresh air to optimise hatchability
Last year I was invited to a layer hatchery that was reporting slightly lower hatchability than its sister hatcheries, despite using eggs from the...
Pulmonary Nocardiosis in turkey poults
Nocardiosis is an opportunistic, noncontagious, pyogranulomatous or suppurative disease of domestic animals, wildlife and people. In domestic animals, it causes mastitis, pneumonia (granulomatous lesions...
Research reveals method to improve Escherichia coli vaccines
A funded research project at the University of Georgia in Athens, Ga. was completed, in which researchers revealed a method to improve Escherichia coli...
Cochlosoma anatis in turkeys
A funded research project at North Carolina State University in Raleigh, N.C. evaluated the pathogenicity of Cochlosoma anatis. The research was made possible in...
Engineering vaccines for multiple strains of IBV
In new work funded by a Biotechnology and Biological Sciences Research Council (BBSRC) researchers at The Pirbright Institute and The Roslin Institute have published...
A new poultry research center at the University of Bristol
A state-of-the art poultry research centre offering specialist, industry-focused research into both laying hen and broiler health, welfare, behavior and productivity has recently been...
