Pirbright’s new Avian Influenza vaccine

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An improved poultry influenza vaccine has been developed by researchers from The Pirbright Institute. The potential vaccine triggers a rapid immune response which protects...

Influenza antibodies made by Pirbright reduce disease in chickens

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Scientists at The Pirbright Institute have engineered synthetic antibody molecules that can be administered to poultry to reduce the symptoms of Influenza, as well as...

Use of comparative genomics to identify vaccine candidates for Campylobacter Jejuni

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Interventions to control and reduce the incidence of Campylobacter jejuni colonization in poultry is important in order to reduce the burden of foodborne illness in humans....

Pathological manifestations of highly pathogenic and predominant Eimeria species in turkeys

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Coccidiosis is caused by intra-cellular enteric protozoan parasites of the genus Eimeria. Eimeria is a gastrointestinal parasite with a complex life cycle involving an...

Overcoming challenges of antibiotic-free production

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Antibiotic use once became a conventional, on-farm practice to prevent health issues and boost growth in poultry. Yet, public health concerns about rising bacteria...

Biosecurity, before the beginning…

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Almost all of us, the poultry people, know what biosecurity is about. For the investors, it means spending lots of money to prevent disasters,...

The relationship between sperm function and diet – Toms are what they eat

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It is well known that cryopreserved semen could be used to regenerate commercial or research poultry lines; however, fertility rates from poultry semen frozen...

Role of dietary calcium in Necrotic Enteritis development and pathogenesis

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USPOULTRY and the USPOULTRY Foundation announce the completion of a funded research project at Texas A&M University in College Station, Texas, in which the...

Managing coccidiosis in birds raised without antibiotics

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For poultry producers to make a profit they must have healthy, uniform sized birds, make sure there are no real or assumed human health...

A multidisciplinary research approach on Avian Influenza in Italy

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The Avian Influenza epidemic of 2016-2017 had been the largest in Europe in more than 10 years. The circulating virus was a Highly Pathogenic...

Holistic view of intestinal health in poultry

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Intestinal health is necessary to maintain efficient and sustainable gastrointestinal tract (GIT) physiology. The GIT has digestive, absorptive, metabolic, immunological and endocrinological functions. This means...

Obtaining the most benefit from an anticoccidial sensitivity test

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The poultry industry has been using the same anticoccidial drugs for the prevention of coccidiosis for several decades. The last approval of a new...

Evaluation of factors that affect susceptibility and control of reovirus-induced viral arthritis in broiler...

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The USPOULTRY Foundation announces the completion of a funded research project at AviServe LLC in Newark, Del. (USA), that has revealed a new tool for...

Female persistency post-peak. Managing fertility and production

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INTRODUCTION Managing breeding stock fertility and egg production is critical to achieving good breeder production and welfare. However, maintaining persistent egg output and hatchability remains...

Bioavailable silicium as feed additive and its beneficial effects throughout poultry production

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Silicium is a naturally occurring trace element that supports bone formation, collagen synthesis, and structural integrity in tissues and eggshell membranes. In poultry, dietary...

The role of feed additives in the protozoal diseases in poultry

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Coccidiosis and histomoniasis are economically significant diseases in chickens and turkeys. Management, vaccination and medication are key tools in the control of these diseases...

The manureshed concept: a solution to poultry litter nutrient recycling?

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Surface waters in the United States are regularly assessed as a part of the Clean Water Act to determine whether the water quality protects...

A synergistic herbal alternative combination: curcumshield vs poultry infections – a broad-spectrum study

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Introduction In the case of bacterial infections, various categories of antibiotics – especially synthetic ones – are widely used as broad-spectrum bacteriostatic and bactericidal agents....

Bacterin usage

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A good vaccination program, along with proper flock management and biosecurity, plays a key role in the health and productivity of broiler breeders. The...

Heat stress causes inhibition of Eimeria replication in broilers

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Eimeria infection is one of the most important diseases affecting poultry production, and is characterized by bloody or watery diarrhea, weight loss, poor feed...

Clinical coccidiosis in broilers with concurrent infection of Eimeria maxima and Eimeria praecox

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Coccidiosis is a complex disease in chickens caused by protozoan parasites in the genus Eimeria. As Eimeria species are ubiquitous in poultry facilities, coccidiosis...

The ABCs of CDT (Clostridial Dermatitis of Turkeys)

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Clostridial Dermatitis of Turkeys (CDT), also referred to as Cellulitis, remains a major disease issue across all geographic regions of the US; the annual...

Macroscopic lesion scoring correlates with gut morphology changes in a newly developed dysbacteriosis model

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Conventional broilers often experience intestinal problems between 20 and 30 days of age, caused by a microbial imbalance in the gut, which is referred...

The importance of gut microbiota in chickens

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Recent expansion in knowledge about the influence of microbiota on health and disease started a major research revolution in the area. Intestinal systems of...

Use of injection syringes in the animal production industry

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Animal health is an important factor to consider, as any disease outbreak can potentially have drastic economical consequences. For this reason, planning and preparing...

Infectious bursal disease viruses may swap genetic material during infection

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Live cell imaging has been used by researchers at The Pirbright Institute to reveal new information about how different strains of infectious bursal disease virus...

Gut health and Coccidiosis

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In poultry, gut health is fundamental and the gastrointestinal tract accounts for twenty percent of the energy expenditure of the whole body. This energy...

Interrupting cholesterol pathway reduces Marek’s disease spread

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In a new discovery, scientists from The Pirbright Institute confirm that cholesterol production and transport play a crucial role in how Marek’s disease virus...

Active and passive Salmonella surveillance systems

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Two surveillance systems have been established in France for the monitoring of antimicrobial resistance (AMR) in Salmonella enterica subsp. enterica isolated from the agro-food...

Update on Infectious Bronchitis in the United States

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Infectious bronchitis infections continued to increase this year in the Ontario broiler, broiler breeder and layer sectors. Infectious bronchitis virus (IBV) can be spread by...

Infectious bronchitis virus shuts down cell stress signals

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A new study from scientists at The Pirbright Institute and collaborators at the University of Surrey provides evidence that infectious bronchitis virus (IBV) can regulate the...

Protecting poultry from Avian Influenza

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The Avian Influenza season is upon us, but how much do you know about Avian Influenza? Do you know how to protect the birds...

Coccidiosis control in broiler breeders with the use of vaccines by Aviagen®

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Coccidiosis is a disease of the intestinal lining, produced by the invasion of the mucosal cells by a very prolific protozoan parasite of the...

Avian influenza diagnostics in foxes provide valuable addition to mammal surveillance

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Research by Wageningen Bioveterinary Research (WBVR) and the Dutch Wildlife Health Centre (DWHC) shows that foxes in the province of Friesland can become infected...

Non-antibiotic intestinal interventions

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As the countdown towards implementation of the FDA’s Guidance for Industry 213 continues, interest in non-antibiotic intestinal interventions has increased. Earliest efforts in this...

In-ovo corticosterone alters body composition in 35 day old chi-cken meat birds

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Increasing evidence suggests early-life exposure to maternal stress can permanently alter thedevelopment of an embryo. Such findings have significant application to the chicken meat...

Enhancing biosecurity using flow analysis and Danish entry concepts

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The term Danish entry is commonly used to describe entryways to livestock buildings that help people enter barns in a relatively bio secure way...

Collaborative regulatory approach can reduce antibiotic use in animal production

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As global concern about the human health threat posed by antimicrobial resistance continues rises, governments continue to introduce legislation to curb antibiotic use in...

Linear Epitope Mapping of B-cell responses following immunization with Avian Reovirus S1133

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Avian reovirus is a causative agents of tenosynovitis and viral arthritis. Commercially available reovirus vaccines do not protect against challenge with emerging variants associated...

The cost of mycoplasma infection in poultry

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Sometimes some Mycoplasma infections cause disease in poultry and this has been extensively studied and worried about by veterinarians, poultry producers and veterinary authorities....

Mycoplasma Synoviae, a technical update

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Mycoplasma are the smallest free-living organisms both in size and number of genes, and unlike many other bacteria, they do not have a cell...

Salmonella prevention strategies and influences of sampling method selection

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Multiple factors can influence both Salmonella prevalence and diversity of Salmonella serogroups detected from both pre and post-harvest samples. Sampling methodologies vary widely when...

How to guard your hatchery against biosecurity threats

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Biosecurity, by simple definition, is a set of procedures undertaken to limit the spread of infectious pathogens to a susceptible population. It is, however,...

Antibiotic-resistance: the contribution of the viruses in GIT microbiome

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The GIT, or rather the gastro intestinal tract, is the organ of the all organism mostly colonized by the microbial population: it hosts more...

A review of novel biological alternatives to antibiotic therapies in poultry

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As poultry producers in Australia continue to limit antibiotic use, increasing numbers of alternative therapies and chemical biosecurity products are being used to overcome...

Gut health

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Gut health and the efficient conversion of feed into its basic components for optimal nutrient absorption is vital for both commercial and turkey breeder...

Infectious Laryngotracheitis (ILT) outbreaks in laying hens in Konya province

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Infectious laryngotracheitis (ILT) epidemic cases characterized with respiratory symptoms, hemorrhagic tracheitis and laryngitis findings were identified in laying hen’s enterprises in Konya province. Ten Lohman-breed...

Animal feed probiotics market expands as antibiotic-free nutrition gains momentum

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The global animal feed probiotics market is undergoing a significant transformation as livestock producers increasingly seek sustainable, science-driven alternatives to conventional growth promoters. Valued...

Profiling Salmonella serotypes through broiler processing

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USPOULTRY and the USPOULTRY Foundation announce the completion of a funded research project at the University of Georgia in which researchers profiled Salmonella serotypes through broiler processing. The...

Biological control of Salmonella in the poultry industry: a European perspective

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Salmonella remains one of the most important foodborne bacterial pathogens worldwide, and is frequently linked with the consumption of contaminated poultry meat and eggs....

Pirbright research to boost vaccine production

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Scientists at the Pirbright Institute have received money, which will enable research into boosting vaccine yields by up to ten fold. The funding was...

Clostridial Dermatitis

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Clostridial Dermatitis is a disease of economic concern in turkeys. Clostridium perfringens and Clostridium septicum have been isolated consistently from dermatitis lesions in turkeys....

Rapid in vitro antimicrobial screening assay against Campylobacter

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Research was undertaken to adapt a multi-well antimicrobial assay as a fast and reliable method to screen large numbers of plant extract treatments against...

Engineering vaccines for multiple strains of IBV

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In new work funded by a Biotechnology and Biological Sciences Research Council (BBSRC) researchers at The Pirbright Institute and The Roslin Institute have published...

Researchers examine the role of APEC in turkey cellulitis

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USPOULTRY and the USPOULTRY Foundation announce the completion of a funded research project at the University of Georgia in Athens, Georgia, in which researchers...

Transcriptomic modifications caused by subclinical necrotic enteritis in broiler chickens

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Phasing out of in-feed antibiotics in the poultry industry has caused necrotic enteritis (NE) to become a primary concern in commercial poultry production in...

A new view of how class I molecules fight diseases

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Classical class I molecules of the major histocompatibility complex (MHC) play crucial roles in defence against viruses. The class I molecules bind pieces of protein...

Water disinfection in poultry farms: a low-cost practice with high impact

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Water is often overlooked as a source of disease risk in poultry farming. Yet, when it comes to biosecurity, drinking water is one of...

Infectious Bursal Disease antibody levels and viral load in commercial broiler chickens

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Infectious bursal disease (IBD) disease is caused by infectious bursal disease virus (IBDV) of the genus Avibirna-viridae and family Birna-viridae. IBDV is found worldwide...

Host and microbial biomarkers for intestinal health and disease in broilers

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New tools can be used to determine the gut health status of animals and to predict animal performance or to make a decision whether...

Pirbright’s livestock coronavirus research

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The Pirbright Institute is aware that misinformation regarding the Institute and its research is circulating on social media following an outbreak of a new...

Avian reovirus, molecular characterization

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Avian reovirus (ARV) is the main cause of viral arthritis and tenosynovitis in chickens and turkeys, triggering economic losses in the poultry industry due...

Detection and quantification of Gallibacterium anatis and Mycoplasma synoviae

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Mycoplasma synoviae is one of the most common preconditions for secondary bacterial infections in poultry. It causes subclinical infections of the upper respiratory tract,...

Major histocompatibility complex and genetic resistance to Infectious Bronchitis Virus

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Infectious bronchitis virus (IBV) is an endemic disease of chickens responsible for considerable economic losses to the poultry industry worldwide. IBV replication leads to...

Frontiers in human and veterinary antibody discovery

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The Pirbright Institute hosted the inaugural Comparative Veterinary Immunology Group (CVIG) meeting Frontiers in Human and Veterinary Antibody discovery on 26 and 27 November,...

Gut health, intestinal innate immunity and performance

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Gut health is a very important determinant for health and performance in particular in production animals. The intestinal innate immune system is pivotal in...

Concurrent infection of Histomonas meleagridis and Eimeria meleagridis in a turkey flock

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Blackhead disease (histomoniasis) in turkeys is one of the protozoan diseases sporadically documented in commercial turkey production facilities. Histomoniasis may induce mild, moderate, or...
Figure 1

Histopathological evaluation of Histomonas meleagridis on ceca and the bursa of Fabricius in turkeys

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Histomoniasis is caused by Histomonas meleagridis, a flagellated protozoan parasite. It causes systemic infection in turkeys and induces characteristic lesions in ceca and liver....

How a single Avian Influenza protein can increase period of infection

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New research led by scientists at The Pirbright Institute has shown how an Avian Infuenza a virus protein, called PB1-F2, is able to shut...

Prevention and control of biofilm in water line systems as part of biosecurity protocols

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This paper does not address the situations in which the microbiological quality of the water has been compromised from the beginning; rather, this paper addresses how drinking...

Salmonella Reading in commercial turkeys. Why now and how?

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Salmonella sp. is one of the most common bacteria associated with foodborne illness in humans. Each year in the United States, foodborne salmonellosis causes...

Reducing antibiotic use without harming profitability is an actual possibility

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Ten million people are at risk due to antibiotic resistance, ensures the “Antimicrobial Resistance Review” published by the United Kingdom government in 2014. Of...

The declining trend of salmonellosis cases in the EU has levelled off

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Cases of Salmonella Enteritidis acquired in the EU have increased in humans by 3% since 2014 says the report, which is compiled by the...

Compatibility of a new multi-strain probiotic with a live-attenuated Salmonella vaccine in chickens

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A pilot study was undertaken to assess the compatibility of a new multistrain probiotic with a live-attenuated Salmonella Typhimurium (ST) vaccine. Experimental units were...

Wooden Breast Disease

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The emergence of Wooden Breast Disease in commercial broiler chickens has been associated with significant economic loss in the poultry industry resulting from severe...

Cecal coccidiosis in turkeys

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Cecal coccidiosis is an important disease that affects the cecal integrity of turkeys and may result in watery feces with flecks of blood. In...

Improving birds’ health by refining their intestinal microbiota health and stability

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Intestinal systems of living organisms are inhabited by a dense community of microorganisms  dominated by bacteria but also containing archea, fungi, protozoa and viruses....

Microbiological consequences of different housing systems for laying hens, with particular reference to Salmonella...

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A significant proportion of human illnesses caused by Salmonella are linked to the consumption of contaminated eggs. In response, substantial government and private industry...

Better than alternatives to antibiotics

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Many poultry flocks require antibiotic treatment, if not every cycle, regularly. Antibiotic alternatives are in great demand, especially in the context of dysbiosis and...

An alternative method to fight Avian Influenza Virus

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A recent project was completed at the University of Iowa, Iowa City, Iowa, in which researchers developed a mobile system that can inactivate Avian...

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